Skip to main content


This medicine is used for the following purposes:

  • gum disease
  • mouth infection
  • mouth ulcers

Brand Name(s): Nupro Chlorhexidine, Oro Clense, Paroex, Peridex, Periogard

Generic Name: Chlorhexidine


After brushing your teeth, swish 15mL of the medicine around in your mouth for 30 seconds, and then spit the medicine out. Do not eat, drink or rinse with anything else for at least 30 minutes.

Keep the medicine at room temperature. Avoid heat and direct light.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

Tell your doctor and pharmacist about all your medicines. Include prescription and over-the-counter medicines, vitamins, and herbal medicines.

This medicine may stain your teeth. Brush and floss your teeth regularly. Ask your dentist about cleaning to remove stains.


Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • dry mouth
  • mouth sores or irritation
  • changes in taste or unpleasant taste

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.


PeaceHealth endeavors to provide comprehensive health care information, however some topics in this database describe services and procedures not offered by our providers or within our facilities because they do not comply with, nor are they condoned by, the ethics policies of our organization.