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Sorafenib Oral Tablet (SORAFENIB - ORAL)

For treating cancer.

Brand Name(s): Nexavar

Generic Name: Sorafenib

Instructions

Take the medicine with 250 mL (1 cup) of water.

Take on empty stomach - 1 hour before or 2 hours after eating.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

You may need to cycle between periods of taking the medicine and taking breaks from the medicine to allow your body to recover. Follow your instructions carefully.

If you forget a dose, just wait. Use the next dose at the usual time. Do not use 2 doses at once.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Avoid touching any powder from a broken tablet. If the powder touches the skin, nose, or eyes, rinse thoroughly with water.

Always wash your hands after handling this medicine.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients on this medicine have developed severe, life-threatening infections. Please speak with your doctor about the risks and benefits of using this medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Please check with your doctor before drinking alcohol while on this medicine.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Do not breastfeed while on this medicine. You may safely start breastfeeding 2 weeks after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women of childbearing age should have a negative pregnancy test before starting this medicine.

Women must use reliable forms of birth control while taking this medicine and for 6 months after stopping to prevent pregnancy.

Men with a female partner who is of childbearing age must use reliable birth control during sexual activity while taking this medicine and for 3 months after stopping to prevent pregnancy.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • acne
  • decreased appetite
  • diarrhea
  • dry mouth
  • lack of energy and tiredness
  • hair loss
  • unusual or long-lasting hoarseness
  • high blood pressure
  • red, burning, or itchy skin
  • weight loss

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • loss of balance
  • bleeding or bruising
  • bone pain
  • chest pain
  • changes in memory, mood, or thinking
  • confusion
  • coughing up blood or vomit that looks like coffee grounds
  • swelling of the legs, feet, and hands
  • fainting
  • fever or chills
  • pain, redness, swelling or blistering on hands, feet or elbows
  • numbness or tingling in hands and feet
  • fast, irregular, or slow heartbeat
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • mood changes
  • mouth sores or irritation
  • muscle pain
  • shortness of breath
  • red, peeling or blistering skin
  • stomach pain
  • bloody or dark, tarry stools
  • light colored stool
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • difficulty adjusting to changes in temperature
  • severe or persistent vomiting
  • sudden or unexplained weight gain
  • slow wound healing

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

 
 

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