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tebentafusp

Pronunciation: te BEN ta fusp

Brand: Kimmtrak

What is the most important information I should know about tebentafusp?

Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.

What is tebentafusp?

Tebentafusp is used to treat adults with a type of cancer in the eye called uveal melanoma that cannot be removed by surgery or has spread.

Your doctor will make sure you have the correct tumor type to be treated with tebentafusp.

Tebentafusp may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving tebentafusp?

Tell your doctor if you have ever had:

  • liver problems.

You may need to have a negative pregnancy test before starting this treatment.

May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using tebentafusp and for at least 1 week after your last dose. Tell your doctor if you become pregnant.

Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

How is tebentafusp given?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Tebentafusp is injected into a vein by a healthcare provider for 15 to 20 minutes. This medicine is usually given every week.

You will be under observation for at least 16 hours following the first three treatments and for at least 30 minutes after future treatments.

Your treatment may be delayed or permanently discontinued if you have certain side effects.

You will need blood tests to check your liver function before you start tebentafusp and during treatment with this medicine.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your tebentafusp injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving tebentafusp?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of tebentafusp?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.

Call your doctor at once if you have:

  • rash, itching, or skin swelling that will not go away; or
  • symptoms of liver problems --right-sided stomach pain or jaundice (yellowing of the skin or eyes).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Common side effects may include:

  • fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, tiredness;
  • feeling dizzy or light-headed;
  • nausea, stomach pain;
  • rash, itching, dry skin;
  • headache;
  • swelling; or
  • abnormal liver function tests.

What other drugs will affect tebentafusp?

Other drugs may affect tebentafusp, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your pharmacist can provide more information about tebentafusp.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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