National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Narcolepsy is not the name you expected.
Narcolepsy is a neurological sleep disorder characterized by chronic, excessive attacks of drowsiness during the day, sometimes called excessive daytime sleepiness (EDS). Attacks of drowsiness may persist for only a few seconds or several minutes. These episodes vary in frequency from a few incidents to several during a single day. Nighttime (nocturnal) sleep patterns may also be disrupted. Three additional symptoms often associated with narcolepsy are sudden extreme muscle weakness (cataplexy), a specific type of hallucination that occurs just before falling asleep or upon awakening, and brief episodes of paralysis while waking up. Narcolepsy also may be associated with "automatic behavior", i.e. doing something automatically without any memory afterward. The incidence of narcolepsy is approximately 1 in 2,000 and most researchers believe that the disorder remains undiagnosed or misdiagnosed in many cases.
There is increasing evidence that narcolepsy is an autoimmune disorder. Autoimmune disorders are caused when the body's immune system mistakenly attacks healthy tissue or cells. In narcolepsy, the immune system destroys certain brain cells that produce a peptide called hypocretin. Hypocretin impacts on many brain functions, but the details of its actions are not yet understood. Why the immune system attacks healthy cells in narcolepsy is unknown and additional environmental and genetic factors may play a role in the development of the disorder.
American Sleep Association
- 1002 Lititz Pike #229
- Lititz, PA 17543
- Email: email@example.com
- Website: http://www.sleepassociation.org/
Center for Narcolepsy, Sleep and Health Research
- College of Nursing, Suite 215
- University of Illinois at Chicago
- Chicago, IL 60612
- Tel: (312)996-5176
- Fax: (312)996-7008
- Email: CNSHR@listserv.uic.edu
- Website: http://www.uic.edu/orgs/cnshr/
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
MedicAlert Foundation International
- 2323 Colorado Avenue
- Turlock, CA 95382
- Tel: (209)669-2401
- Fax: (209)669-2456
- Tel: (888)633-4298
- Email: Inquiries@medicalert.org
- Website: http://www.medicalert.org
- 4002 Brookhill Road
- Baltimore, MD 21215
- Email: firstname.lastname@example.org
- Website: https://nicer.ngo
NIH/National Institute of Neurological Disorders and Stroke
- P.O. Box 5801
- Bethesda, MD 20824
- Tel: (301)496-5751
- Fax: (301)402-2186
- Tel: (800)352-9424
- Website: http://www.ninds.nih.gov/
- Montefiore Medical Center
- 111 East 210th Street
- Bronx, NY 10467
- Tel: (718)920-6799
- Fax: (718)654-9580
- Email: MGoswami@NarcolepsyInstitute.org
- Website: http://www.narcolepsyinstitute.org
Narcolepsy Network, Inc.
- 129 Waterwheel Lane
- North Kingstown, RI 2852
- Tel: (401)667-2523
- Fax: (401)633-6567
- Tel: (888)292-6522
- Email: email@example.com
- Website: http://www.narcolepsynetwork.org
National Sleep Foundation
- 1010 N. Glebe Road
- Suite 310
- Arlington, VA 22201
- Tel: (703)243-1697
- Email: firstname.lastname@example.org
- Website: http://www.sleepfoundation.org
Tri-State Sleep Disorders Center
- 1275 E. Kemper Rd.
- Cincinnati, OH 45246
- Tel: (513)671-3101
- Fax: (513)671-4159
- Tel: (800)838-4322
- Email: email@example.com
- Website: http://www.tristatesleep.com
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
Last Updated: 7/15/2015
Copyright 2012 National Organization for Rare Disorders, Inc.
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