Amniotic Band Syndrome

National Organization for Rare Disorders, Inc.

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It is possible that the main title of the report Amniotic Band Syndrome is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

Amniotic band syndrome is a well-known condition potentially associated with a variety of different birth defects. It is important to note that no two cases of amniotic band syndrome are exactly alike and that the associated symptoms are highly variable. The severity of amniotic band syndrome can range from a single, isolated finding to multiple, disfiguring complications. The arms and legs are most often affected. The head and face and, in some cases, various internal organs can also be affected. The exact cause of amniotic band syndrome is unknown and controversial. Two main theories have been proposed to explain the development of the disorder. One theory attributes the disorder to causes that arise internally within the fetus (intrinsic theory); the other theory attributes the disorder to causes acting upon the fetus externally (extrinsic theory). It is likely that both internal and external factors can cause amniotic band syndrome, and that the cause of the disorder in one infant may be different from the cause in another infant.

Supporting Organizations

Birth Defect Research for Children, Inc.

976 Lake Baldwin Lane
Orlando, FL 32814
Tel: (407)895-0802

Cleft Lip and Palate Foundation of Smiles

2044 Michael Ave SW
Wyoming, MI 49509
Tel: (616)329-1335

Fetal Hope Foundation

9786 South Holland Street
Littleton, CO 80127
Tel: (303)932-0553
Tel: (877)789-4673

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311

NIH/National Institute of Child Health and Human Development

31 Center Dr
Building 31, Room 2A32
Bethesda, MD 20892
Fax: (866)760-5947
Tel: (800)370-2943

Newlife Foundation for Disabled Children

Newlife Centre
Hemlock Way
Staffordshire, WS11 7GF
United Kingdom
Tel: 1543462777
Fax: 1543468999


P.O. Box 54
Cornwall, TR13 8WD
United Kingdom
Tel: 8451306225
Fax: 8451300262

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  5/10/2012
Copyright  2012 National Organization for Rare Disorders, Inc.