Hairy Cell Leukemia

National Organization for Rare Disorders, Inc.

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Important
It is possible that the main title of the report Hairy Cell Leukemia is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

General Discussion

Hairy cell leukemia (HCL) is a rare type of blood cancer characterized by abnormal changes in white blood cells known as B lymphocytes. The bone marrow creates too many of these defective cells, known as "hairy cells" because of the thin hair-like projections found on their surface. Overproduction and accumulation of hairy cells causes a deficiency of normal blood cells (pancytopenia), including an abnormal decrease of certain white blood cells (neutrophils [neutropenia]) and certain red blood cells (platelets [thrombocytopenia]). Affected individuals usually exhibit fatigue, weakness, fever, weight loss, and/or abdominal discomfort due to an abnormally enlarged spleen (splenomegaly). In addition, affected individuals may have a slightly enlarged liver (hepatomegaly) and may be unusually susceptible to bruising and/or severe infection. The exact cause of hairy cell leukemia is not known.

Supporting Organizations

American Cancer Society, Inc.

250 Williams NW St
Ste 6000
Atlanta, GA 30303
USA
Tel: (404)320-3333
Tel: (800)227-2345
Website: http://www.cancer.org

Cancer Support Community

1050 17th St NW Suite 500
Washington, DC 20036
Tel: (202)659-9709
Fax: (202)974-7999
Tel: (888)793-9355
Website: http://www.cancersupportcommunity.org/

Children's Leukemia Research Association

585 Stewart Avenue, Suite 18
Garden City, NY 11530
Tel: (516)222-1944
Fax: (516)222-0457
Email: info@childrensleukemia.org
Website: http://www.childrensleukemia.org

Friends of Cancer Research

1800 M Street NW
Suite 1050 South
Washington, DC 20036
Tel: (202)944-6700
Email: info@focr.org
Website: http://www.focr.org

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
Website: http://rarediseases.info.nih.gov/GARD/

Hairy Cell Leukemia Research Foundation

575 Madison Ave
10 FLoor
New York, NY 10022
USA
Tel: (224) 355-7201
Email: info@hairycellleukemia.org
Website: http://www.hairycellleukemia.org

Leukemia & Lymphoma Society

3 International Drive
Suite 200
Rye Brook, NY 10573
Tel: (914)949-5213
Fax: (914)949-6691
Tel: (800)955-4572
Email: infocenter@LLS.org
Website: http://www.LLS.org

Livestrong Foundation

2201 E. Sixth Street
Austin, TX 78702
Tel: (512)236-8820
Fax: (512)236-8482
Tel: (877)236-8820
Email: media@livestrong.org
Website: http://www.livestrong.org

National Cancer Institute

6116 Executive Blvd Suite 300
Bethesda, MD 20892-8322
USA
Tel: (301)435-3848
Tel: (800)422-6237
Email: cancergovstaff@mail.nih.gov
Website: http://www.cancer.gov

OncoLink: The University of Pennsylvania Cancer Center Resource

3400 Spruce Street
2 Donner
Philadelphia, PA 19104-4283
USA
Tel: (215)349-8895
Fax: (215)349-5445
Email: hampshire@uphs.upenn.edu
Website: http://www.oncolink.upenn.edu

Rare Cancer Alliance

1649 North Pacana Way
Green Valley, AZ 85614
USA
Website: http://www.rare-cancer.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  10/25/2013
Copyright  2013 National Organization for Rare Disorders, Inc.