Familial Adenomatous Polyposis

National Organization for Rare Disorders, Inc.

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Important
It is possible that the main title of the report Familial Adenomatous Polyposis is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

Familial adenomatous polyposis (FAP) is a rare inherited cancer predisposition syndrome characterized by hundreds to thousands of precancerous colorectal polyps (adenomatous polyps). If left untreated, affected individuals inevitably develop cancer of the colon and/or rectum at a relatively young age. FAP is inherited in an autosomal dominant manner and caused by abnormalities (mutations) in the APC gene. Mutations in the APC gene cause a group of polyposis conditions that have overlapping features: familial adenomatous polyposis, Gardner syndrome, Turcot syndrome and attenuated FAP.

Supporting Organizations

American Cancer Society, Inc.

250 Williams NW St
Ste 6000
Atlanta, GA 30303
USA
Tel: (404)320-3333
Tel: (800)227-2345
Website: http://www.cancer.org

CORE

3 St. Andrews Place
London, NW1 4LB
United Kingdom
Tel: 2074860341
Fax: 2072242012
Email: info@corecharity.org.uk
Website: http://www.corecharity.org.uk

Cancer Support Community

1050 17th St NW Suite 500
Washington, DC 20036
Tel: (202)659-9709
Fax: (202)974-7999
Tel: (888)793-9355
Website: http://www.cancersupportcommunity.org/

Cancer.Net

American Society of Clinical Oncology
2318 Mill Road Suite 800
Alexandria, VA 22314
Tel: (571)483-1780
Fax: (571)366-9537
Tel: (888)651-3038
Email: contactus@cancer.net
Website: http://www.cancer.net/

Desmoid Tumor Research Foundation

P.O. Box 273
Suffern, NY 10901
Tel: (914)262-6595
Fax: (845)369-8302
Email: marlene@dtrf.org
Website: http://www.dtrf.org

Familial GI Cancer Registry

Mt. Sinai Hospital
Joseph and Wolf Lebovic Health Complex
Ontario, M5T 3L9
Canada
Tel: 4165964200
Fax: 4165855024
Email: zcc@mtsinai.on.ca
Website: http://www.mountsinai.on.ca/care/fgicr

Friends of Cancer Research

1800 M Street NW
Suite 1050 South
Washington, DC 20036
Tel: (202)944-6700
Email: info@focr.org
Website: http://www.focr.org

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
Website: http://rarediseases.info.nih.gov/GARD/

Johns Hopkins Hereditary Colorectal Cancer Registry

Johns Hopkins Hospital
1830 East Monument Stree
Baltimore, MD 21205
Tel: (410)955-2635
Fax: (410)614-8337
Tel: (888)772-6566
Email: hccregistry@jhmi.edu
Website: http://www.hopkins-gi.org

M. D. Anderson Cancer Center Hereditary Colorectal Cancer Registry

Dept of Gastrointestinal Oncology
1515 Holcombe Boulevard
Houston, TX 77030
Tel: (713)792-3245
Fax: (713)745-1163
Tel: (877)632-6789
Email: hcc-editor@mdacc.tmc.edu
Website: http://www.mdanderson.org/about-us/index.html

National Cancer Institute

6116 Executive Blvd Suite 300
Bethesda, MD 20892-8322
USA
Tel: (301)435-3848
Tel: (800)422-6237
Email: cancergovstaff@mail.nih.gov
Website: http://www.cancer.gov

OncoLink: The University of Pennsylvania Cancer Center Resource

3400 Spruce Street
2 Donner
Philadelphia, PA 19104-4283
USA
Tel: (215)349-8895
Fax: (215)349-5445
Email: hampshire@uphs.upenn.edu
Website: http://www.oncolink.upenn.edu

Rare Cancer Alliance

1649 North Pacana Way
Green Valley, AZ 85614
USA
Website: http://www.rare-cancer.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  1/27/2014
Copyright  2014 National Organization for Rare Disorders, Inc.