National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Ewing Sarcoma is not the name you expected.
Ewing sarcoma is a rare bone tumor that occurs most often in adolescents. It can also arise outside of the bone in soft tissue (extraosseous Ewing sarcoma). Ewing sarcoma is related to another type of tumor known as primitive neuroectodermal tumor (PNET). Researchers have learned that these tumors are associated with the same chromosomal abnormality (balanced reciprocal translocation) and share many physiological characteristics. Consequently, these tumors are sometimes collectively classified as the Ewing family of tumors (EFT). This general term encompasses Ewing sarcoma of bone, extraosseous Ewing sarcoma, primitive neuroectodermal tumor, and Askin's tumor (a tumor of the chest wall). Ewing sarcoma of bone accounts for approximately 70 percent of the tumors in this family. Generally, the term Ewing sarcoma is preferred because, despite the different names, it is one tumor, molecularly. Ewing sarcoma of bone most often affects the long bone of the legs (femur) and flat bones such as those found in the pelvis and chest well. Ewing sarcoma is an aggressive cancer that may spread (metastasize) to the lungs, other bones, and bone marrow potentially causing life-threatening complications. The exact cause of these tumors is unknown.
Ewing sarcoma was first described in the medical literature in 1921 by Dr. James Ewing. Ewing sarcoma is the second most common primary bone tumor in children and accounts for approximately 2% of all childhood cancer diagnoses.
NORD's report on Ewing sarcoma is a detailed summary of the main aspects of this rare disorder. The National Cancer Institute offers comprehensive, in-depth information on this disorder, which is available at,
For patients: http://www.cancer.gov/cancertopics/pdq/treatment/ewings/Patient
For healthcare professionals: http://www.cancer.gov/cancertopics/pdq/treatment/ewings/HealthProfessional
American Cancer Society, Inc.
- 250 Williams NW St
- Ste 6000
- Atlanta, GA 30303
- Tel: (404)320-3333
- Tel: (800)227-2345
- Website: http://www.cancer.org
- 76 Ellsworth Street
- San Francisco, CA 94110
- Tel: (415)826-0474
- Email: email@example.com
- Website: http://www.beatsarcoma.org/
- American Society of Clinical Oncology
- 2318 Mill Road Suite 800
- Alexandria, VA 22314
- Tel: (571)483-1780
- Fax: (571)366-9537
- Tel: (888)651-3038
- Email: firstname.lastname@example.org
- Website: http://www.cancer.net/
Friends of Cancer Research
- 1800 M Street NW
- Suite 1050 South
- Washington, DC 22202
- Tel: (202)944-6700
- Email: email@example.com
- Website: http://www.focr.org
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
National Cancer Institute
- 6116 Executive Blvd Suite 300
- Bethesda, MD 20892-8322
- Tel: (301)435-3848
- Tel: (800)422-6237
- Email: firstname.lastname@example.org
- Website: http://www.cancer.gov
National Coalition for Cancer Survivorship
- 1010 Wayne Avenue
- 7th Floor
- Silver Spring, MD 20910
- Tel: (301)650-9127
- Fax: (301)565-9670
- Tel: (888)650-9127
- Email: email@example.com
- Website: http://www.canceradvocacy.org/
Northwest Sarcoma Foundation
- P.O. Box 91460
- Portland, OR 97291
- Tel: (503)954-5740
- Email: firstname.lastname@example.org
- Website: http://www.nwsarcoma.org
OncoLink: The University of Pennsylvania Cancer Center Resource
- 3400 Spruce Street
- 2 Donner
- Philadelphia, PA 19104-4283
- Tel: (215)349-8895
- Fax: (215)349-5445
- Email: email@example.com
- Website: http://www.oncolink.upenn.edu
Rare Cancer Alliance
- 1649 North Pacana Way
- Green Valley, AZ 85614
- Website: http://www.rare-cancer.org
- 775 East Blithedale 334
- Mill Valley, CA 94941
- Tel: (415)381-7236
- Fax: (415)381-7235
- Email: firstname.lastname@example.org
- Website: http://www.sarcomaalliance.org
Sarcoma Foundation of America
- 9899 Main Street Ste 204
- Damascus, MD 20872
- Tel: (301)253-8687
- Fax: (301)253-8690
- Email: email@example.com
- Website: http://www.curesarcoma.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
Last Updated: 1/14/2013
Copyright 2013 National Organization for Rare Disorders, Inc.
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