Cri du Chat Syndrome

National Organization for Rare Disorders, Inc.

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Important
It is possible that the main title of the report Cri du Chat Syndrome is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

Cri du chat syndrome (CdCS or 5p-) is a rare genetic disorder in which a variable portion of the short arm of chromosome 5 is missing or deleted (monosomic). Symptoms vary greatly from case to case depending upon the exact size and location of the deleted genetic material. Common symptoms include a distinctive cry that resembles the mewing of a cat, characteristic facial features, slow growth, and microcephaly, a condition that indicates that head circumference is smaller than would be expected for an infant's age and sex. Affected children also exhibit delays in the acquisition of skills requiring the coordination of muscular and mental activities (psychomotor disability) and moderate to severe intellectual disability. Additional symptoms affecting different organ systems of the body can also occur. Most cases are thought arise from spontaneous (de novo) genetic errors very early in embryonic development.

Supporting Organizations

5P-Society

PO Box 268
Lakewood, CA 90714
USA
Tel: (562)804-4506
Fax: (562)920-5240
Tel: (888)970-0777
Email: director@fivepminus.org
Website: http://www.fivepminus.org

Chromosome Disorder Outreach, Inc.

P.O. Box 724
Boca Raton, FL 33429-0724
USA
Tel: (561)395-4252
Fax: (561)395-4252
Email: info@chromodisorder.org
Website: http://www.chromodisorder.org/

Cleft Lip and Palate Foundation of Smiles

2044 Michael Ave SW
Wyoming, MI 49509
Tel: (616)329-1335
Email: Rachel@cleftsmile.org
Website: http://www.cleftsmile.org

Cri Du Chat Syndrome Support Group

PO Box 3408
Norwich, NR3 3WE
United Kingdom
Tel: 8450942725
Fax: 1455841680
Email: office@criduchat.org.uk
Website: http://www.criduchat.org.uk/

Department of Human Genetics/Cri du Chat

Medical College of Virginia
P.O. Box 980033
Richmond, VA 23298
Tel: (804)828-8116
Fax: (804)828-8801

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
Website: http://rarediseases.info.nih.gov/GARD/

March of Dimes

1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)997-4488
Fax: (914)997-4763
Email: AskUs@marchofdimes.org or preguntas@nacersano.org
Website: http://www.marchofdimes.org and nacersano.org

The Arc

1825 K Street NW, Suite 1200
Washington, DC 20006
Tel: (202)534-3700
Fax: (202)534-3731
Tel: (800)433-5255
Email: info@thearc.org
Website: http://www.thearc.org

UNIQUE - Rare Chromosome Disorder Support Group

G1 The Stables
Station Road West
Oxted, RH8 9EE
United Kingdom
Tel: 0044 (0)1883 723356
Email: info@rarechromo.org
Website: http://www.rarechromo.org/html/home.asp

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  6/14/2011
Copyright  2011 National Organization for Rare Disorders, Inc.