butorphanol (nasal)

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Pronunciation: byoo TOR fa nole

Brand: Stadol NS

What is the most important information I should know about butorphanol nasal?

Butorphanol can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Butorphanol may also be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medicine in a place where others cannot get to it.

MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how butorphanol will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with butorphanol nasal.

What is butorphanol nasal?

Butorphanol is an opioid pain medication. An opioid is sometimes called a narcotic.

Butorphanol is used to treat moderate to severe pain.

Butorphanol may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using butorphanol nasal?

You should not use this medicine if you are allergic to butorphanol.

Some medicines can interact with butorphanol and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure this medicine is safe for you, tell your doctor if you have:

  • any type of breathing problem or lung disease;
  • liver or kidney disease;
  • a history of head injury, brain tumor, or seizures;
  • heart disease, high blood pressure, recent heart attack; or
  • a history of drug abuse, alcohol addiction, or mental illness.

It is not known whether this medicine will harm an unborn baby. If you use butorphanol nasal while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Butorphanol nasal can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Older adults may be more sensitive to the effects of this medication.

How should I use butorphanol nasal?

Follow all directions on your prescription label. Butorphanol can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never use butorphanol nasal in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Butorphanol may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away butorphanol is against the law.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

The usual dose of butorphanol nasal for pain is 1 spray into one nostril every 3 to 4 hours. Your dose may be different. Follow your doctor's instructions carefully.

For best results, blow your nose before using the nasal spray.

Before using the spray for the first time, you must prime the spray pump. Remove the protective clip and pump 7 or 8 times into the air until a fine mist appears. Prime the spray pump any time you have not used your nasal spray for longer than 48 hours.

Do not stop using butorphanol nasal suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using butorphanol nasal.

Store at room temperature away from moisture and heat.

After you are finished using this medication, remove the cap and rinse out the bottle under running water. Throw away the bottle and cap where children or pets cannot get to them.

What happens if I miss a dose?

Since butorphanol nasal is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A butorphanol overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, and fainting.

What should I avoid while using butorphanol nasal?

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with butorphanol nasal.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how butorphanol will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

What are the possible side effects of butorphanol nasal?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • weak or shallow breathing, slow heart rate;
  • pounding or uneven heartbeats;
  • problems with urination;
  • tremors, numbness or tingling;
  • severe dizziness, confusion, feeling like you are floating;
  • a light-headed feeling, like you might pass out;
  • infertility, missed menstrual periods;
  • impotence, sexual problems, loss of interest in sex;
  • dangerously high blood pressure --severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats; or
  • low cortisol levels -- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects include:

  • drowsiness, dizziness;
  • sleep problems (insomnia);
  • nausea, vomiting; or
  • stuffy nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect butorphanol nasal?

Some medicines can cause unwanted or dangerous effects when used with butorphanol. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

Using this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using butorphanol nasal with a sleeping pill, other narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with butorphanol nasal, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about butorphanol nasal.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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