PerphenazineSkip to the navigation
Perphenazine is used to treat symptoms associated with psychiatric disorders, as well as severe nausea and vomiting in adults. It is in a class of drugs known as phenothiazine neuroleptics.
Common brand names:Trilafon
Summary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
Reduce Side Effects
Phenothiazine drugs similar to perphenazine can cause changes in heart activity in some people, which might be prevented by supplementing with coenzyme Q10.1 , 2 Therefore, some health practitioners may recommend coenzyme Q10 supplementation to people taking perphenazine.The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Potential Negative Interaction
1. Kishi T, Makino K, Okamoto T, et al. In Yamamura Y, Folkers K, Ito Y, eds. Biochemical and Clinical Aspects of Coenzyme Q, Volume 2. Amsterdam: Elsevier/North Holland Biomedical Press, 1980, 139-57.
2. Werbach MR. Foundations of Nutritional Medicine. Tarzana, CA: Third Line Press, Inc., 1997, 212.
Last Review: 03-18-2015
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