Drug Information

Ketoprofen is used to treat rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is in a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs).

Common brand names:

Orudis, Oruvail

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • White Willow

    Willow bark (Salix alba) contains salicin, which is related to aspirin. Both salicin and aspirin produce anti-inflammatory effects after they have been converted to salicylic acid in the body. The interaction between salicylic acid and ketoprofen is complex. While it may enhance the effectiveness of ketoprofen, salicylic acid also speeds its elimination from the body.1 Consequently, people taking ketoprofen should avoid herbal products that contain willow bark.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.


1. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 3285-8.