Drug Information

Amphotericin B is an antifungal drug. Topically, it is used to treat skin yeast infections. Intravenously, it is used to treat a variety of life-threatening fungal infections.

Common brand names:

Amphocin, Fungizone

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • Magnesium

    Amphotericin B has been reported to increase urinary excretion of magnesium.1 It remains unclear whether it is important for people taking this drug to supplement magnesium.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • none

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.


1. McLean R. Magnesium and its therapeutic uses: A review. Am J Med 1994;96: 63-76.