Acute chest syndrome is a lung-related complication of sickle cell disease that can lower the levels of oxygen in the blood and can be life-threatening. Repeat occurrences of acute chest syndrome can cause lung damage. This condition develops more often in young children but is usually more severe in adults.
Symptoms of acute chest syndrome can include:
Symptoms require emergency evaluation and treatment. Because a person with acute chest syndrome can deteriorate rapidly, a hospital stay is usually needed. Some cases are mild and will need little more than careful observation. More severe cases may need treatment in an intensive care unit (ICU) of the hospital.
Although its cause is not fully understood, acute chest syndrome is more likely to develop after:
Treatment of acute chest syndrome includes:
Other Works Consulted
- National Heart, Lung, and Blood Institute, National Institutes of Health (2002). The Management of Sickle Cell Disease (NIH Publication No. 02-2117). Available online: http://www.nhlbi.nih.gov/health/prof/blood/sickle/.
- Steinberg MH (2012). Sickle cell disease and other hemoglobinopathies. In L Goldman, A Shafer, eds., Goldman's Cecil Medicine, 24th ed., pp. 1066–1075. Philadelphia: Saunders.
|Primary Medical Reviewer||E. Gregory Thompson, MD - Internal Medicine|
|Specialist Medical Reviewer||Martin Steinberg, MD - Hematology|
|Last Revised||October 1, 2012|
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