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letrozole

Pronunciation: LET roe zol

Brand: Femara

Letrozole 2.5 mg-TEV

round, yellow, imprinted with TEVA, B1

Image of Letrozole 2.5 mg-TEV
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What is the most important information I should know about letrozole?

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Letrozole can harm an unborn baby or cause birth defects. Do not use if you are pregnant.

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You should not use this medication if you are allergic to letrozole, or if you have not gone completely through menopause.

Before taking letrozole, tell your doctor if you have osteoporosis, high cholesterol, or liver disease (especially cirrhosis).

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This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

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To be sure letrozole is helping your condition, your blood may need to be tested often. Your bone mineral density may also need to be checked. Visit your doctor regularly.

Tell your doctor about all other medicines you use, especially tamoxifen (Soltamox).

What is letrozole?

Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Letrozole is used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.

Letrozole may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using letrozole?

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You should not use this medication if you are allergic to letrozole, or if you have not gone completely through menopause.

To make sure you can safely take letrozole, tell your doctor if you have any of these other conditions:

  • osteoporosis;
  • high cholesterol; or
  • liver disease (especially cirrhosis).
Multum nopreg

FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use letrozole if you are pregnant, or if you have not gone completely through menopause. Tell your doctor right away if you become pregnant during treatment.

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It is not known whether letrozole passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using letrozole.

How should I take letrozole?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Letrozole is usually taken once per day, or once every other day. Follow your doctor's instructions.

You may take letrozole with or without food.

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To be sure this medication is helping your condition, your blood may need to be tested often. Your bone mineral density may also need to be checked. Visit your doctor regularly.

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Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking letrozole?

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This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of letrozole?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • dizziness, drowsiness, weakness, tired feeling;
  • hot flashes, warmth in your face or chest;
  • flushing (warmth, redness, or tingly feeling);
  • headache;
  • nausea, constipation;
  • bone pain, muscle or joint pain;
  • numbness, tingling, weakness, or stiffness in your hand or fingers;
  • pain in your hand that spreads to your arm, wrist, forearm, or shoulder;
  • night sweats; or
  • weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect letrozole?

Tell your doctor about all other medicines you use, especially tamoxifen (Soltamox).

There may be other drugs that can interact with letrozole. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about letrozole.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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