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dexbrompheniramine and pseudoephedrine

Pronunciation: dex brome fen IR a meen/soo doe e FED rin

Brand: Conex, Drixoral, Drixoral Cold and Allergy

What is the most important information I should know about dexbrompheniramine and pseudoephedrine?

Multum emt

You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate.

Multum donot

Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

What is dexbrompheniramine and pseudoephedrine?

Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dexbrompheniramine and pseudoephedrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Dexbrompheniramine and pseudoephedrine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking dexbrompheniramine and pseudoephedrine?

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Multum emt

You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate.

Multum donot

Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or a thyroid disorder.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:

  • a colostomy or ileostomy;
  • diabetes;
  • liver or kidney disease;
  • epilepsy or other seizure disorder;
  • cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;
  • enlarged prostate or urination problems;
  • pheochromocytoma (an adrenal gland tumor); or
  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).
Multum nopreg

FDA pregnancy category C. It is not known whether dexbrompheniramine and pseudoephedrine will harm an unborn baby. Do not use this medicine without medical advice if you are pregnant.

Multum nobrfeed

Dexbrompheniramine and pseudoephedrine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without medical advice if you are breast-feeding a baby.

Artificially sweetened liquid medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

How should I take dexbrompheniramine and pseudoephedrine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.

Multum donot

Do not take for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.

Multum nochild

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Multum nocrush

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Multum emt

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Multum rt

Store at room temperature away from moisture and heat. Do not allow the liquid form of this medicine to freeze.

What happens if I miss a dose?

Since dexbrompheniramine and pseudoephedrine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking dexbrompheniramine and pseudoephedrine?

Multum dizzy

This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Multum noalcohol

Drinking alcohol can increase certain side effects of dexbrompheniramine.

Multum donot

Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine. Antihistamines and decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine or decongestant.

What are the possible side effects of dexbrompheniramine and pseudoephedrine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Stop using this medicine and call your doctor at once if you have:

  • fast or uneven heart rate;
  • mood changes;
  • tremor, seizure (convulsions);
  • easy bruising or bleeding, unusual weakness;
  • little or no urinating;
  • feeling short of breath; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

Other common side effects may include:

  • dizziness, drowsiness;
  • dry mouth, nose, or throat;
  • constipation;
  • blurred vision; or
  • feeling nervous or restless.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect dexbrompheniramine and pseudoephedrine?

Multum dizzy

Taking this medicine with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before taking dexbrompheniramine and pseudoephedrine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Ask a doctor or pharmacist if it is safe for you to take dexbrompheniramine and pseudoephedrine if you are also using any of the following drugs:

  • topiramate;
  • zonisamide;
  • bladder or urinary medicines such as darifenacin, tolterodine, solifenacin;
  • bronchodilators such as ipratropium or tiotropium;
  • medication for Parkinson's disease;
  • medication to treat excess stomach acid, stomach ulcer, nausea, motion sickness, or irritable bowel syndrome; or
  • other cold or allergy medicine that contains an antihistamine.

This list is not complete. Other drugs may interact with dexbrompheniramine and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about dexbrompheniramine and pseudoephedrine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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