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Fludarabine is available as an oral and intravenous (IV) medicine.
Fludarabine is an antimetabolite medicine. It causes cell death by interfering with the way genetic material (DNA) in the cell multiplies.
Fludarabine is an effective treatment for chronic lymphocytic leukemia (CLL) that has not responded to other types of chemotherapy, such as chlorambucil or cyclophosphamide. Studies are ongoing to find out the safety and effectiveness of fludarabine in people who have not received other types of chemotherapy or who are responding to other types of chemotherapy.
Side effects are common with fludarabine and can include:
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
You may not be able to become pregnant or father a child after taking this medicine. Discuss fertility with your doctor before starting treatment.
Fludarabine can cause birth defects. Do not use this medicine if you are pregnant or if you wish to become pregnant or father a child while you are taking it.
Fludarabine can interact with many other medicines. Be sure that your doctor has a complete list of all prescription and nonprescription medicines you are taking.
Do not drink alcoholic beverages or take medicines containing aspirin while being treated with fludarabine, because these can cause bleeding from your stomach.
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