X-linked agammaglobulinemia (XLA) is an inherited disorder that
occurs only in boys, in which they have extremely low levels of certain
antibodies needed to fight infection. As a result, they have frequent
infections, most often of the lungs, sinuses, and bones.
X-linked agammaglobulinemia usually first appears in infant boys 6
to 9 months old. Boys with agammaglobulinemia need regular treatment with
antibiotics or immunoglobulin (IG) to help prevent serious infection.
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