Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2 Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
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The developers of methoxyisoflavone, a member of the flavonoid family, claim that it builds bone and muscle without the side effects seen with hormones. One trial found that athletes who took it reduced their body fat more significantly than those taking placebo.
Methoxyisoflavone is a member of the family flavonoids (isoflavones). In a U.S. Patent, the developers of this substance claim, based on preliminary animal research, that it possesses anabolic (muscle-building and bone-building) effects without the side effects seen with either androgenic (male) hormones or estrogenic (female) hormones.2 A preliminary controlled trial found that strength-training athletes who took 800 mg per day of methoxyisoflavone for eight weeks experienced a significantly greater reduction in percentage body fat than those who took a placebo.3 Double-blind research is needed to confirm these findings. The U.S. patent also claims methoxyisoflavone reduces appetite and lowers blood cholesterol levels. Whether this claim is true has not yet been demonstrated in published scientific research.
Manufacturers of methoxyisoflavone recommend 200 to 400 mg twice a day.
Several substances similar to methoxyisoflavone are found in many plants and some foods, including soybeans. Whether methoxyisoflavone itself is found in nature is unknown.
Methoxyisoflavone is not an essential nutrient, so no deficiencies are possible.
1. Feuer L, Farkas L, Nogradi M, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. United States Patent 4,163,746, August 7, 1979.
2. Feuer L, Farkas L, Nogradi M, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. United States Patent 4,163,746, August 7, 1979.
3. Incledon T, Gammeren DV, Antonio JA. The effects of 5-methylisoflavone on body composition and performance in college aged men. Med Sci Sports Exer 2001;33(5 suppl):S338 [abstract].
Last Review: 05-01-2013
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