Some athletes say that ornithine alpha-ketoglutarate helps improve muscle growth.
Ornithine alpha-ketoglutarate (OKG) is used by the body to make many substances related to cell growth and repair. It has been used in medical research to treat severe burns, improve healing after surgery, and other clinical situations. Unfortunately, no research has explored the effects of OKG in athletes.
OKG is formed from the amino acids ornithine and glutamine and is believed to facilitate muscle growth by enhancing the body’s release of anabolic hormones. While this effect has been found in studies on hospitalized patients and elderly people,1 , 2 no studies on muscle growth in athletes using OKG have been published.
Although the amino acids that comprise OKG are present in protein foods such as meat and poultry and fish, the OKG compound is found only in supplements.
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