The optimal level of intake is not known, but some doctors recommend 200 to 400 mcg of sulforaphane daily from broccoli-sprout extracts.
Sulforaphane is found in highest concentrations in broccoli sprouts, but it is also found in mature broccoli and other cruciferous vegetables, such as cauliflower, cabbage, and kale.
Sulforaphane is not an essential nutrient, and thus no deficiency state exists.
Sulforaphane and dietary consumption of cruciferous vegetables does interact with drug detoxifying enzymes.2 People taking prescription drugs should therefore consult a doctor before taking sulforaphane or broccoli-sprout extracts.
1. Zhang Y, Talalay P, Cho CG, Posner GH. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci 1992;89:2399–403.
2. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett 1997;114:169–70.
Last Review: 05-01-2013
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