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3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
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1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Benign Prostatic Hyperplasia
126 mg three times daily
Rye pollen extract has been shown to improve BHP symptoms.
Rye pollen extract has improved the symptoms of BPH in preliminary trials.1 , 2 , 3 Double-blind trials have also reported that rye pollen extract is effective for reducing symptoms of BPH4 , 5 This rye pollen extract was shown to be comparable in effect to an amino acid mixture used for BPH in a double-blind study.6 A double-blind comparison with pygeum resulted in significant subjective improvement in 78% of those given the rye pollen extract compared with 55% using pygeum.7 Research on this commercial rye pollen extract has used three to six tablets, or four capsules, per day; the effect of other pollens in men with prostate conditions has not yet been studied.
Two tablets of flower pollen extract twice per day
An extract of flower pollen, derived primarily from rye, may improve symptoms of chronic prostatitis and prostadynia.
An extract of flower pollen, derived primarily from rye, may improve symptoms of chronic prostatitis and prostadynia. In a small, uncontrolled trial, men with chronic NBP or prostadynia given two tablets of flower pollen extract twice daily for up to 18 months reported complete or marked improvement in symptoms.8 In a larger, uncontrolled trial, one tablet three times daily for six months produced a favorable response in 80% of the men based on symptoms, laboratory tests, and doctor evaluations.9 Men who did not respond in this study were found to have structural abnormalities of the urinary tract, suggesting that uncomplicated prostate conditions are more likely to respond to flower pollen. Additional uncontrolled studies support the effectiveness of flower pollen extract,10 , 11 , 12 but no controlled research has been published.
Research on a proprietary rye pollen extract has used 3 to 6 tablets, or 4 capsules, per day.
Most noncultivated plants produce pollen. Commercial pollen is collected from bees returning to their hives (bee pollen) or may be directly harvested with machines (flower pollen). It is not clear which plants produce the most effective pollens. In addition to rye, other common pollens used are timothy grass, corn, and pine.
Since pollen is not an essential bodily constituent, deficiencies do not occur.
Many people have allergies to inhaled pollens. Allergic reactions to ingested pollen (some of them quite serious) have also been reported.2 3 4 Otherwise, no significant adverse effects have been reported.
1. Horii A, Iwai S, Maekawa M, Tsujita M. Clinical evaluation of Cernilton in the treatment of the benign prostatic hypertrophy. Hinyokika Kiyo 1985;31:739–45 (in Japanese).
2. Ueda K, Jinno H, Tsujimura S. Clinical evaluation of Cernilton® on benign prostatic hyperplasia. Hinyokika Kiyo 1985;31:187–91 [in Japanese].
3. Hayashi J, Mitsui H, Yamakawa G, et al. Clinical evaluation of Cernilton in benign prostatic hypertrophy. Hinyokika Kiyo 1986;32:135–41 [in Japanese].
4. Buck AC, Cox R, Rees RW, et al. Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, cernilton. A double-blind, placebo-controlled study. Br J Urol 1990;66:398–404.
5. Becker H, Ebeling L. Conservative therapy of benign prostatic hyperplasia (BPH) with Cernilton. Urologe (B) 1988;28:301–6 [in German].
6. Maekawa M, Kishimoto T, Yasumoto R, et al. Clinical evaluation of Cernilton on benign prostatic hypertrophy—a multiple center double-blind study with Paraprost. Hinyokika Kiyo 1990;36:495–516 [in Japanese].
7. Dutkiewicz S. Usefulness of Cernilton® in the treatment of benign prostatic hyperplasia. Int Urol Nephrol 1996;28:49–53.
8. Buck AC, Rees RW, Ebeling L. Treatment of chronic prostatitis and prostatodynia with pollen extract. Br J Urol 1989;64:496–9.
9. Rugendorff EW, Weidner W, Ebeling L, Buck AC. Results of treatment with pollen extract (Cernilton N) in chronic prostatitis and prostatodynia. Br J Urol 1993;71:433–8.
10. Jodai A, Maruta N, Shimomae E, et al. A long-term therapeutic experience with Cernilton in chronic prostatitis. Hinyokika Kiyo 1988;34:561–8 [in Japanese].
11. Suzuki T, Kurokawa K, Mashimo T, et al. Clinical effect of Cernilton in chronic prostatitis. Hinyokika Kiyo 1992;38:489–94 [in Japanese].
12. Ohkoshi M, Kawamura N, Nagakubo I. Clinical evaluation of Cernilton in chronic prostatitis. Jpn J Clin Urol 1967;21:73–6.
Last Review: 05-01-2013
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.
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