Topic Contents

Drug Information

Tretinoin

Drug Information

Tretinoin is a slightly altered version of vitamin A. Topical tretinoin is available in cream, gel, and liquid forms to treat acne, other skin conditions, and some forms of skin cancer. Tretinoin is also available in oral capsules used to induce remission in people with acute promyelocytic leukemia.

Common brand names:

Altinac, Renova, Retin-A, Avita

Summary of Interactions with Vitamins, Herbs, & Foods

What Are Nutrient Interactions

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

none

Reduce Side Effects

none

Support Medicine

none

Reduces Effectiveness

none

Potential Negative Interaction

Vitamin A

Large amounts of vitamin A can cause side effects, and oral tretinoin can cause similar side effects. Combining vitamin A with oral tretinoin is likely to increase the risk of side effects. People taking oral tretinoin should probably not take more than 10,000 IU of supplemental vitamin A per day.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Explanation Required

none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

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Last Review: 11-07-2012

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2013.

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