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Sucralfate

Drug Information

Sucralfate is used to treat intestinal ulcers, and it is a type of drug known as a polysaccharide antipeptic.

Common brand names:

Carafate

Summary of Interactions with Vitamins, Herbs, & Foods

What Are Nutrient Interactions

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

Calcium

Slight increases in blood calcium levels may occur in people taking sucralfate, which could be aggravated by calcium supplementation.¹ Therefore, people taking calcium supplements and sucralfate should have their blood calcium levels monitored by their healthcare practitioner and may need to avoid calcium supplementation.
Phosphorus

People taking sucralfate may develop lower than normal blood levels of phosphorus.² A 42-year-old woman who took sucralfate for two weeks experienced bone pain that was caused by low phosphorus levels. The bone pain disappeared after she stopped taking the drug and began supplementing with phosphorus.³ Individuals taking sucralfate should have their blood phosphorus levels monitored regularly by their healthcare practitioner and may need to take supplemental phosphorus.

Reduce Side Effects

none

Support Medicine

none

Reduces Effectiveness

none

Potential Negative Interaction

none

Explanation Required

none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Vucelic B, Hadzic N, Gragas J, Puretic Z. Changes in serum phosphorus, calcium, and alkaline phosphatase due to sucralfate. Int J Clin Pharmacol Ther Toxicol 1986;24:93–6.

2. Vucelic B, Hadzic N, Gragas J, Puretic Z. Changes in serum phosphorus, calcium, and alkaline phosphatase due to sucralfate. Int J Clin Pharmacol Ther Toxicol 1986;24:93–6.

3. Chines A, Pacifici R. Antacid and sucralfate-induced hypophosphatemic osteomalacia: a case report and review of the literature. Calcif Tissue Int 1990;47:291–5.

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Last Review: 02-05-2013

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.

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