Lindane lotion is used topically to treat scabies;lindane shampoo is used to treat head and pubic lice. They are used in situations where treatment with other drugs has failed or cannot be tolerated by the individual.
Test tube studies reveal that vitamin E protects white blood cells from damage caused by lindane.1 Lindane is known to promote the formation of tumors,2 and more research is needed to determine whether vitamin E, when applied at the same time as lindane, can prevent this adverse effect.
Applying oils, creams, and ointments at the same time as lindane may enhance the absorption of the drug through the skin.3 Therefore, to avoid side effects, other drugs and herbal formulas in cream or ointment form should be applied at other times during the day.
1. Podstawka U, Grabarczyk M, Kopec-Szlezak J. Vitamin E protects human leucocytes against toxic effects of lindane in vitro. Mater Med Pol 1991;23:285–9.
2. Dich J, Zahn SH, Hanberg A, Adami HO. Pesticides and cancer. Cancer Causes Control 1997;8:420–43.
3. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc.,2000, 504–5.
Last Review: 11-07-2012
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