Topic Contents

Lamivudine

Drug Information

Lamivudine is used to treat human immunodeficiency virus (HIV) infection and is in a class of drugs known as antivirals.

Common brand names:

Epivir, Epivir HBV

Summary of Interactions with Vitamins, Herbs, & Foods

What Are Nutrient Interactions

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

none

Reduce Side Effects

none

Support Medicine

Sho-saiko-to

Test tube studies show that the herbal combination sho-saiko-to enhances the antiviral activity of lamivudine.¹ Sho-saiko-to contains extracts of seven herbs, including Bupleuri radix, Pinelliae tuber, Scutellariae radix, Zizyphi fructus, ginseng (Ginseng radix), licorice (Glycyrrhizae radix), and ginger (Zingibers rhizoma). Controlled studies are needed to determine whether taking sho-saiko-to might enhance the beneficial effects of lamivudine.

The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Reduces Effectiveness

none

Potential Negative Interaction

none

Explanation Required

none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Piras G, Makino M, Baba M. Sho-saiko-to, a traditional kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiol Immunol 1997;41:835–9.

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Last Review: 11-07-2012

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