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Frovatriptan

Drug Information

Common brand names:

Frova

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • none

Support Medicine

  • High-Fat

    Though food does not significantly interfere with the overall effectiveness of triptans, it may slow the onset of action of sumatriptan and rizatriptan. Therefore, these drugs are best taken on an empty stomach. However, taking eletriptan with a high-fat meal increases overall absorption of the drug.1

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Reduces Effectiveness

  • none

Potential Negative Interaction

  • none

Explanation Required 

  • 5-HTP

    Triptans work by stimulating serotonin receptors in the brain. 5-HTP (5-Hydroxytryptophan) and L-tryptophan are converted to serotonin in the brain, and taking them at the same time as 5-HT1 agonists could increase unwanted side effects. However, at the time of this writing there are no known interactions with 5-HT1 agonists and 5-HTP or L-tryptophan.3

  • L-Tryptophan

    Triptans work by stimulating serotonin receptors in the brain. 5-HTP (5-Hydroxytryptophan) and L-tryptophan are converted to serotonin in the brain, and taking them at the same time as 5-HT1 agonists could increase unwanted side effects. However, at the time of this writing there are no known interactions with 5-HT1 agonists and 5-HTP or L-tryptophan.4

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

References

1. Wolters Kluwer Health, Inc. Facts and Comparisons[online] 2007 [cited 2007 Feb]. Available from http://www.factsandcomparisons.com.

2. Wolters Kluwer Health, Inc. Facts and Comparisons[online] 2007 [cited 2007 Feb]. Available from http://www.factsandcomparisons.com.

3. Wolters Kluwer Health, Inc. Facts and Comparisons[online] 2007 [cited 2007 Feb]. Available from http://www.factsandcomparisons.com.

4. Wolters Kluwer Health, Inc. Facts and Comparisons[online] 2007 [cited 2007 Feb]. Available from http://www.factsandcomparisons.com.

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