Leiomyosarcoma, Inferior Vena Cava
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Leiomyosarcoma, Inferior Vena Cava is not the name you expected.
Leiomyosarcoma of the inferior vena cava is an extremely rare malignant (cancerous) tumor arising from the smooth muscle lining the walls of the large vein that carries blood from the lower body to the heart (inferior vena cava). There are essentially two types of muscles in the body - voluntary and involuntary. Smooth muscles are involuntary muscles - the brain has no conscious control over them. Smooth muscles react involuntarily in response to various stimuli. For example, the smooth muscle in walls of blood vessels contracts to help regulate blood flow.
Leiomyosarcomas are a form of cancer. The term "cancer" refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread (metastasize) to distant bodily tissues or organs via the bloodstream, the lymphatic system, or other means. Different forms of cancer, including leiomyosarcomas, are graded according to certain histological parameters evaluated microscopically and this grade (low, intermediate, or high) gives the clinician an indication of the potential clinical aggressiveness of the tumor.
Leiomyosarcoma is classified as a soft tissue sarcoma. Sarcomas are malignant tumors that arise from the connective tissue, which connects, supports and surrounds various structures and organs in the body. Soft tissue includes fat, muscle, nerve, tendons, tissue surrounding the joints (synovial tissue), and blood and lymph vessels. The exact cause of sarcomas including leiomyosarcomas is unknown.
American Cancer Society, Inc.
250 Williams NW St
Atlanta, GA 30303
National Cancer Institute
6116 Executive Blvd Suite 300
Bethesda, MD 20892-8322
OncoLink: The University of Pennsylvania Cancer Center Resource
3400 Spruce Street
Philadelphia, PA 19104-4283
Sarcoma Foundation of America
9899 Main Street Ste 204
Damascus, MD 20872
775 East Blithedale 334
Mill Valley, CA 94941
Rare Cancer Alliance
1649 North Pacana Way
Green Valley, AZ 85614
Northwest Sarcoma Foundation
P.O. Box 91460
Portland, OR 97291
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email email@example.com
Last Updated: 8/2/2010
Copyright 2010 National Organization for Rare Disorders, Inc.