Skip Navigation

Search Knowledgebase

fosamprenavir

Pronunciation: FOS am pren a veer

Brand: Lexiva

Lexiva 700 mg

oblong, pink, imprinted with GX LL7

Image of Lexiva 700 mg
slide 1 of 1
    

What is the most important information I should know about fosamprenavir?

Multum donot

Some medicines can cause unwanted or dangerous effects when used with fosamprenavir. Your doctor may need to change your treatment plan if you use any of the following drugs: alfuzosin, cisapride, delavirdine, lovastatin, simvastatin, midazolam, triazolam, pimozide, rifampin, sildenafil (for treating pulmonary arterial hypertension), St. John's wort, or an ergot medicine (dihydroergotamine, ergotamine, ergonovine, methylergonovine).

Do not take fosamprenavir together with another HIV medicine called ritonavir if you are also using flecainide or propafenone to treat a heart rhythm disorder. Ask your doctor about taking a different heart rhythm medication during treatment with fosamprenavir.

What is fosamprenavir?

Fosamprenavir is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

Fosamprenavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Fosamprenavir is not a cure for HIV or AIDS.

Fosamprenavir may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking fosamprenavir?

Multum donot

You should not take this medication if you have ever had a severe allergic reaction to fosamprenavir.

Some medicines can cause unwanted or dangerous effects when used with fosamprenavir. Your doctor may need to change your treatment plan if you use any of the following drugs: alfuzosin, cisapride, delavirdine, lovastatin, simvastatin, midazolam, triazolam, pimozide, rifampin, sildenafil (for treating pulmonary arterial hypertension), St. John's wort, or an ergot medicine (dihydroergotamine, ergotamine, ergonovine, methylergonovine).

Do not take fosamprenavir together with another HIV medicine called ritonavir if you are also using flecainide or propafenone to treat a heart rhythm disorder. Ask your doctor about taking a different heart rhythm medication during treatment with fosamprenavir.

To make sure fosamprenavir is safe for you, tell your doctor if you have:

  • liver disease;
  • kidney disease;
  • diabetes;
  • a bleeding disorder such as hemophilia;
  • heart disease, history of heart attack;
  • an allergy to sulfa drugs;
  • high cholesterol or triglycerides; or
  • if you have ever used a protease inhibitor in the past.
Multum nopreg

FDA pregnancy category C. It is not known whether fosamprenavir will harm an unborn baby. However, HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection. Tell your doctor if you become pregnant during treatment.

Your name may need to be listed on an antiviral pregnancy registry when you start using this medication.

Multum bcp

Taking fosamprenavir together with ritonavir and also using birth control pills can increase your risk of liver problems. Ask your doctor about using non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking fosamprenavir and ritonavir.

Multum nobrfeed

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Fosamprenavir should not be given to an infant younger than 4 weeks (28 days) old.

How should I take fosamprenavir?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Fosamprenavir tablets can be taken with or without food.

Fosamprenavir liquid should be taken with food in children and without food in adults.

Multum shake

Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If a child is taking this medication, tell your doctor if the child has any changes in weight. Fosamprenavir doses are based on weight in children.

Use fosamprenavir regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

While using fosamprenavir, you may need frequent blood tests at your doctor's office.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Multum rt

Store fosamprenavir tablets at room temperature away from moisture and heat.

Multum refig

You may store fosamprenavir liquid in the refrigerator but do not allow it to freeze.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking fosamprenavir?

Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

What are the possible side effects of fosamprenavir?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Stop taking fosamprenavir and call your doctor at once if you have:

  • chest pain or pressure, tight feeling in your neck or jaw, pain spreading to your arm or shoulder;
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;
  • increased urination or extreme thirst;
  • sudden and severe pain in your lower back or side, blood in your urine, pain or burning when you urinate;
  • signs of a new infection, such as fever or chills, cough, flu symptoms, easy bruising or bleeding;
  • rapid heart rate, increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia);
  • diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex;
  • swelling in your neck or throat (enlarged thyroid);
  • muscle weakness, tired feeling, joint or muscle pain, feeling short of breath;
  • weakness or prickly feeling in your fingers or toes;
  • problems with walking, breathing, speech, swallowing, or eye movement;
  • loss of bladder or bowel control;
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects of fosamprenavir may include:

  • mild nausea, vomiting, stomach pain;
  • numbness or tingling, especially around your mouth;
  • headache, mood changes; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect fosamprenavir?

Multum donot

Many other drugs can cause serious or life-threatening drug interactions if you use them while taking fosamprenavir. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with fosamprenavir, especially:

  • atorvastatin;
  • bosentan;
  • colchicine;
  • rifabutin;
  • antifungal medication--itraconazole, ketoconazole;
  • an antidepressant--amitriptyline, imipramine, paroxetine, trazodone;
  • any other HIV /AIDS medication;
  • a blood thinner such as warfarin (Coumadin);
  • drugs that weaken the immune system such as cancer medicine, steroids, and medicines to prevent organ transplant rejection
  • heart rhythm medication--amiodarone, lidocaine, quinidine;
  • heart or blood pressure medicine--amlodipine, diltiazem, nifedipine, verapamil, and others;
  • the hepatitis C medications boceprevir or telaprevir;
  • insulin or oral diabetes medication;
  • medicines to treat erectile dysfunction--avanafil, sildenafil, tadalafil, vardenafil;
  • seizure medications--carbamazepine, phenobarbital, phenytoin (Dilantin); or
  • stomach acid reducers--cimetidine, famotidine, nizatidine, ranitidine (Zantac).

This list is not complete and many other drugs can interact with fosamprenavir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about fosamprenavir.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 9.01. Revision date: 4/1/2013.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.