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Drug Information

Mifepristone, also known as RU486, is used to induce abortion, and is classified both as a progesterone and a glucocorticosteroid receptor antagonist. It has also been used experimentally to treat Cushing’s syndrome (hyperfunctioning adrenal glands), breast cancer, and glaucoma.

Common brand names:


Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • Modified Shenghua Tang

    The most common side effect of mifepristone is excess vaginal bleeding. One controlled study showed that drinking modified shenghua tang (a tea made from bupleurum, angelica, ligusticum, peach kernel, baked ginger, and leonurus) greatly reduced the number of days that bleeding occurred following mifepristone therapy.1

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • none

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.


1. Sun L, Pan J. Treating colporrhagia after medical abortion with modified shenghua tang. J Tradit Chin Med 1996;16:263-6.

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