Why It Is Done
Direct Coombs test
The direct Coombs test finds antibodies attached to your
own red blood cells. The antibodies may be those your body made because of
disease or those you get in a blood transfusion.
The direct Coombs test also may be done on a newborn baby whose
mother has
Rh-negative blood. The test shows whether
the mother has made antibodies and if the antibodies have moved through the
placenta to her baby.
Indirect Coombs test
The indirect Coombs test finds antibodies that are in your blood but not attached to your red blood cells. The
indirect Coombs test is commonly done to find antibodies in a recipient's or
donor's blood before a transfusion.
An Rh antibody titer, is
done early in pregnancy to check a woman's blood type. If she is Rh-negative, steps can
be taken to protect the baby.