Medications
Nephrotic syndrome is usually successfully treated
with a combination of medicines.
Medication Choices
Medicines to treat nephrotic syndrome include:
- Corticosteroids, such as prednisone or
prednisolone, to reduce swelling.
- Albumin, to restore
blood volume.
- Diuretics, such as bumetanide or
furosemide, to help maintain fluid balance.
- Cyclophosphamide,
cyclosporine, or CellCept, when treatment with corticosteroids is not
successful.
Most children are successfully treated with corticosteroids,
though relapses are common.7
Clinical trials are ongoing to test more effective
medicines for the treatment of steroid-resistant (relapsing) nephrotic
syndrome. Ask your doctor about information on clinical trials if treatment has
not successfully controlled your nephrotic syndrome. To participate in a
clinical trial, you may need to travel to a large treatment center.
What To Think About
Most children who have nephrotic syndrome do well with treatment
and have a normal life expectancy. Children older than age 12 at the time of
diagnosis and adults who also have diabetes or high blood pressure do not
respond as well to treatment as do children younger than 12.