Medications
Nephrotic syndrome is usually successfully treated with a combination of
medicines.
Medication Choices
Medicines to treat nephrotic syndrome include:
- Corticosteroids, such as prednisone or
prednisolone, to reduce swelling.
- Albumin, to restore
blood volume.
- Diuretics, such as bumetanide or
furosemide, to help maintain fluid balance.
- Cyclophosphamide,
cyclosporine, or CellCept, when treatment with corticosteroids is not
successful.
Most children are successfully treated with
corticosteroids, though relapses are common.7
Clinical trials are ongoing to test
more effective medicines for the treatment of steroid-resistant (relapsing)
nephrotic syndrome. Ask your doctor about information on clinical trials if
treatment has not successfully controlled your nephrotic syndrome. To
participate in a clinical trial, you may need to travel to a large treatment
center.
What To Think About
Most children who have nephrotic
syndrome do well with treatment and have a normal life expectancy. Children
older than age 12 at the time of diagnosis and adults who also have diabetes or
high blood pressure do not respond as well to treatment as do children younger
than 12.