Heart failure occurs when your heart loses its ability to pump blood
efficiently. Decreased pumping function by the left ventricle occurs in two
major ways:
- Systolic heart failure.
Your ventricle does not squeeze forcefully enough during systole, which
is the phase of your heartbeat when your heart pumps blood.
- Diastolic heart failure.Your ventricle does not relax properly
during diastole, which is the phase of your heartbeat when your heart fills
with blood.
What happens in systolic heart failure?
Systolic heart failure occurs when your left ventricle pumps less blood than
normal. There are many different problems that can cause your left ventricle to
pump less efficiently during systole. For example, if part of your heart muscle
is damaged from a heart attack, it may not be able to contract as well as it
usually would.
What happens in diastolic heart failure?
Diastolic heart failure occurs when less blood fills the left ventricle
before it contracts again. As with systolic heart failure, there are many
different problems that can impair your left ventricle's ability to fill
properly with blood during diastole. For example, chronic high blood pressure
can cause your heart muscle to become stiff or thickened so that it cannot
relax properly, which limits how much blood fills the left ventricle.
What is high-output heart failure? A small
percentage of people with heart failure actually have a problem called
high-output heart failure. With high-output heart failure, the body's need for
blood is unusually high. The heart may be working well otherwise, but it cannot
produce a high enough cardiac output to keep up with this extra need. Less than
1% of people with heart failure have high-output heart failure.
There are a variety of conditions that can significantly increase the
body's need for blood and oxygen, resulting in high-output heart failure. These
conditions include
anemia,
hyperthyroidism, and pregnancy. Although the causes of
high-output heart failure are different from the cause of other types of heart
failure, the end result is the same: Your heart is not supplying enough blood
to meet your body's needs. High-output heart failure results in the same
classic symptoms of heart failure, including fatigue and shortness of
breath.
What is right-sided heart failure? Most people
develop heart failure because of a problem with the left ventricle. However,
reduced function of the right ventricle can also occur in heart failure. As
blood begins to back up behind the failing left ventricle and into the lungs,
it will become increasingly difficult for the right ventricle to pump returning
blood through the lungs. Like the left ventricle, the right ventricle will
eventually weaken and begin to fail. While left-sided heart failure is
typically the cause of right-sided heart failure, other conditions, such as
certain lung diseases, can cause the right ventricle to fail even when there is
no problem with your left ventricle.
People with heart failure can have more than one type of heart
failure. For example, left-sided heart failure can cause right-sided heart
failure. In such cases, heart failure does not have more than one cause, but
rather the heart failure is affecting the heart in more than one way. In other
cases, there may be two separate problems, such as mitral regurgitation causing
left-sided heart failure but tricuspid regurgitation causing right-sided heart
failure.
How can systolic dysfunction cause heart
failure? A low
ejection fraction is the hallmark of systolic heart
failure. Determining your ejection fraction is essential for effectively
diagnosing and treating your heart failure. Systolic dysfunction means that
your heart is not functioning well during systole, the phase of your heartbeat
when your heart squeezes (contracts) and pumps blood.
You may develop systolic dysfunction when another serious condition,
such as coronary artery disease, damages your heart. As your body attempts to
compensate for your systolic dysfunction, your heart may be damaged further,
leading to more severe dysfunction and ultimately to heart failure. Systolic
dysfunction most commonly affects the left ventricle, the chamber of your heart
that pumps blood out to your body, but it can also affect your right
ventricle.
What is my ejection fraction? Your ejection
fraction measures how efficiently your left ventricle is pumping blood. During
diastole, the phase of the heartbeat between contractions, your left ventricle
fills with a certain amount of blood. During systole, the ventricle contracts
and pumps a certain portion of that blood out to your body. Your ejection
fraction is the percentage of the blood that fills your left ventricle during
diastole that is then pumped out to the body during systole.
In a healthy heart, the ejection fraction is about 60% or more. In
systolic heart failure, the ejection fraction is less than 60%, and it can be
as low as 10% to 15%. If you have systolic heart failure, the volume of blood
pumped with each heartbeat (the stroke volume) is reduced in addition to the
percentage of blood that is pumped with each heartbeat (the ejection
fraction).
How does my heart compensate for systolic
dysfunction? Your heart may be able to compensate for systolic heart
failure by getting more blood into your ventricle. Unfortunately, this effort
to compensate for systolic dysfunction by left ventricular dilatation can
damage your heart further, leading to more severe dysfunction. If your ejection
fraction drops below 40% to 50%, doctors will consider you to have systolic
dysfunction. While you can have a low ejection fraction without developing
heart failure, the more systolic dysfunction you have, the more likely you are
to develop heart failure.
How can diastolic dysfunction cause heart failure?
Diastole is the phase of your heartbeat when your heart relaxes and
fills with blood. Diastolic dysfunction means that your left ventricle cannot
relax properly during diastole. As a result, your ventricle does not fill with
enough blood before it pumps. If diastolic dysfunction is severe enough, it can
lead to heart failure.
Diastolic heart failure happens because the left ventricle's muscle
becomes too stiff or thickened. To compensate for stiff heart muscle, your
heart has to increase the pressure inside the ventricle to properly fill the
ventricle. Over time, this increased filling causes blood to build up inside
the left atrium and eventually into the lungs, which leads to fluid congestion
and the symptoms of heart failure.
Why doesn't diastolic heart failure affect my
ejection fraction? In diastolic heart failure, your left ventricle may
pump well during systole; it is just not filling with enough blood during
diastole. Your ventricle may have a normal ejection fraction, but it has less
blood inside it to pump out. As a result, your ventricle pumps out less blood
with each beat (what doctors call a decrease in stroke volume).