Dactylitis (hand-foot syndrome) and sickle cell diseaseDactylitis is severe pain that affects the bones of the
hands, the feet, or both. It's often the first symptom of
sickle cell disease in babies. About half of infants
born with sickle cell disease have at least one episode of dactylitis by the
age of 2 years. Dactylitis rarely occurs after age 4.1 Dactylitis is caused by blocked blood
circulation. Symptoms include extreme pain and tenderness, usually with
swelling. An episode may last 1 to 2 weeks.
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