Hepatitis D (delta) virus infection

Infection with the hepatitis D virus (HDV), or delta agent, occurs only in people who are already infected with the hepatitis B virus (HBV).

  • HDV infection may make HBV infection more severe.
  • In people who have long-term (chronic) HBV infection, hepatitis D virus infection can make liver disease worse, or it can cause a person who did not have symptoms before to develop liver problems more rapidly.
  • Some people who have hepatitis D also have severe hepatitis B.
  • Vaccination against hepatitis B will prevent hepatitis D virus infection.
  • Hepatitis D virus infection is rare in the United States.


Author: Maria G. Essig, MS, ELSLast Updated: October 15, 2007
Medical Review: Kathleen Romito, MD - Family Medicine
W. Thomas London, MD - Hepatology

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