Calcium D-glucarate

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Also indexed as:

D-Glucarate, D-Glucaric Acid, Glucaric Acid

Calcium D-glucarate is the calcium salt of D-glucaric acid, a natural substance found in many fruits and vegetables.

Where is it found?

Calcium D-glucarate is available in capsules and tablets. Foods high in glucaric acid (a form of calcium D-glucarate) include apples, Brussels sprouts, broccoli, cabbage, and bean sprouts.¹

Health Concerns

Calcium D-glucarate has been used in connection with the following conditions (refer to the individual health concern for complete information):

Rating	Health Concerns
	Cancer
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. An herb is primarily supported by traditional use, or the herb or supplement has little scientific support and/or minimal health benefit.

Deficiency Symptoms

Who is likely to be deficient?

Calcium D-glucarate is not an essential nutrient, and thus no deficiency state exists.

Dosage

How much is usually taken?

Manufacturers of calcium D-glucarate recommend a daily intake of 200 to 400 mg.

Side Effects

Are there any side effects or interactions?

No side effects have been reported with calcium D-glucarate. Although there are no known drug interactions, many drugs (especially hormones) are metabolized in the liver by binding to glucuronic acid. It is therefore possible that taking calcium D-glucarate could increase the elimination of certain drugs or hormones from the body, thereby reducing their effectiveness. If you are taking any prescription medication, please consult your physician or pharmacist before taking calcium D-glucarate.

At the time of writing, there were no well-known drug interactions with calcium D-glucarate.

References

1. Dwivedi C, Heck WJ, Downie AA, et al. Effect of calcium glucarate on beta-glucuronidase activity and glucarate content of certain vegetables and fruits. Biochem Med Metab Biol 1990;43:83-92.

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Last Review: 09-01-2007

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