Raloxifene

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Evista

Raloxifene is a type of drug called a selective estrogen receptor modulator (SERM). It is used to prevent osteoporosis in women after menopause.

Herbs

Summary of Interactions for Raloxifene

Depletion or interference	Phytoestrogens
Adverse interaction	None known
Side effect reduction/prevention	None known
Supportive interaction	None known
Reduced drug absorption/bioavailability	None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Herbs

Formononetin

Some chemicals called phytoestrogens, found naturally in plants, have estrogen-like activity; and some people use these phytoestrogens from dietary sources or from supplements to prevent or treat hormone-related health problems. In test tube studies, the estrogenic activity of one phytoestrogen, formononetin, was blocked by raloxifene.¹ Further research is necessary to determine the overall effect of raloxifene on formononetin and other phytoestrogens in humans.

References

1. Ruh MF, Taylor JA, Howlett AC, Welshons WV. Failure of cannabinoid compounds to stimulate estrogen receptors. Biochem Pharmacol 1997;53:35-41.

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Last Review: 09-01-2007

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