Bisoprolol

Alternative Medicine
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Also indexed as:

Zebeta

Combination List

Combination drug:

Bisoprolol is a beta-blocker drug used to lower blood pressure in people with hypertension.

Herbs

Summary of Interactions for Bisoprolol

Depletion or interferenceNone known
Adverse interactionHigh-potassium foods*
Pleurisy root
Potassium supplements*
Side effect reduction/preventionNone known
Supportive interactionNone known
Reduced drug absorption/bioavailabilityNone known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Supplements

Potassium

Some beta-adrenergic blockers (called "nonselective" beta blockers) decrease the uptake of potassium from the blood into the cells,1 leading to excess potassium in the blood, a potentially dangerous condition known as hyperkalemia.2 People taking beta-blockers should therefore avoid taking potassium supplements, or eating large quantities of fruit (e.g., bananas), unless directed to do so by their doctor.

Interactions with Herbs

Pleurisy root

As pleurisy root and other plants in the Aesclepius species contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as bisoprolol.3

Other Interactions

Food

Bisoprolol may be taken with or without food.4

Alcohol

Bisoprolol may cause drowsiness, dizziness, lightheadedness, or blurred vision.5 Alcohol may intensify these effects and increase the risk of accidental injury. To prevent problems, people taking bisoprolol should avoid alcohol.

References

  1. Rosa RM, Silva P, Young JB, et al. Adrenergic modulation of extrarenal potassium disposal. N Engl J Med 1980;302:431-4.
  2. Lundborg P. The effect of adrenergic blockade on potassium concentrations in different conditions. Acta Med Scand Suppl 1983;672:121-6 [review].
  3. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: Pharmaceutical Press, 1996, 213-4.
  4. Leopold G, Pabst J, Ungethum W, Buhring KU. Basic pharmacokinetics of bisoprolol, a new highly beta 1-selective adrenoceptor antagonist. J Clin Pharmacol 1986;26:616-21.
  5. Threlkeld DS, ed. Diuretics and Cardiovasculars, Beta-Adrenergic Blocking Agents. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1993, 158o.

Last Review: 09-01-2007

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.


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Topic Contents
 Combination List
 Herbs
 Interactions with Supplements
 Interactions with Herbs
 Other Interactions
 References