Parasites

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Also indexed as:

Giardia, Pinworms, Worms

Overview

What you need to know

Food and water: sources of life -but also possible sources of parasites. Rid yourself of these intestinal pests and the infections they cause. According to research or other evidence, the following self-care steps may be helpful:

• Stay hydrated
• When diarrhea strikes, replace lost fluids and replenish electrolytes by drinking sports drinks or other rehydration solutions

• Make prevention a priority
• When traveling to areas where parasitic infections are common, don't drink the tap water and avoid uncooked foods, foods prepared by street vendors, ice, and fruits that cannot be peeled

• Try a natural treatment
• Talk to a professional about treating parasitic infections with natural antimicrobials, such as propolis, and berberine-containing herbs, including barberry, Oregon grape, goldenseal, and goldthread (Coptis chinensis)

• Visit your healthcare provider
• Ask about medical treatments that are effective against parasites

These recommendations are not comprehensive and are not intended to replace the advice of your doctor or pharmacist. Continue reading the full parasites article for more in-depth, fully-referenced information on medicines, vitamins, herbs, and dietary and lifestyle changes that may be helpful.

About parasites

Parasites are organisms larger than yeast or bacteria that can cause infection, usually in the intestines. The most common parasites to infect humans in the United States and Canada are giardia (Giardia lamblia), Entamoeba histolytica, cryptosporidium (Cryptosporidium spp.), roundworm (Ascaris lumbricoides), hookworm (Ancylostoma duodenale and Necator americanus), pinworm (Enterobius vermicularis), and tapeworm (Taenia spp.).

Infection with parasites can be life-threatening in people with severe impairment of immune function. People should consult a physician if they suspect a parasitic infection.

Check list

Product ratings for parasites

Rating	Nutritional Supplements	Herbs
	Propolis	Papaya seeds Berberine Ipecac Myrrh (for schistosomiasis)
		Anise Barberry Black walnut Chaparral Cloves Curled mint Garlic Goldenseal Goldthread Male fern Oregon grape Pumpkin seeds Sweet Annie Tansy Wormseed Wormwood
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. An herb is primarily supported by traditional use, or the herb or supplement has little scientific support and/or minimal health benefit.

Symptoms

What are the symptoms?

Parasite infections can lead to a variety of symptoms, including gas, bloating, diarrhea, weight loss, abdominal cramping and pain, constipation, nausea, vomiting, loss of appetite, fever, rash, cough, itching anus, and bloody or foul-smelling stools.

Diet

Dietary changes that may be helpful

When traveling in developing countries, people should avoid drinking tap water and eating uncooked foods, foods prepared by street vendors, ice, and fruits that cannot be peeled. All of these are potential sources of parasitic infection. People should not drink untreated stream water while camping, as it is frequently almost invariably contaminated with giardia, even in the United States. Undercooked fish, meat and poultry can also contain parasites.

Supplements

Vitamins that may be helpful

Propolis is a resinous substance collected by bees from the leaf buds and bark of trees, especially poplar and conifer trees. The antimicrobial properties of propolis may help protect against parasitic infections in the gastrointestinal tract. One preliminary trial of propolis extract for children and adults with giardiasis showed a 52% rate of successful parasite elimination in children and a 60% elimination rate in adults (amount not stated).¹ These results are not as impressive as those achieved with conventional drugs for giardiasis, though, so propolis should not be used as the sole therapy for parasites without first consulting a physician about available medical treatment.

Are there any side effects or interactions?

Refer to the individual supplement for information about any side effects or interactions.

Herbs

Herbs that may be helpful

Berberine is derived from several plants, including barberry, Oregon grape, goldenseal, and goldthread (Coptis chinensis). Preliminary trials have shown that berberine can be used successfully to treat giardia infections.^{2, 3} In addition, test tube studies show that berberine kills amoebae, although it is not known whether this effect occurs in humans.⁴ The amount required is approximately 200 mg three times per day for an adult-a level high enough to potentially cause side effects. Therefore, berberine should not be used without consulting a healthcare provider.

Seeds of the papaya fruit, Carica papaya, have been used in folk medicine to treat intestinal parasites. In a preliminary trial conducted in Nigeria, treatment with papaya seeds eradicated intestinal parasites in 71 to 100% of children, depending on the parasite being treated. Parasites that were successfully eradicated were A. lumbricoides, E. histolytica, N. americanus, S. stercoralis, T. trichiura, G. lamblia, and T. saginata. Treatment consisted of a single administration of 20 ml of an elixir containing 4 grams of air-dried and blended papaya seeds.⁵

Emetine and other alkaloids in ipecac kill several types of parasites, including amoeba, pinworms, and tapeworms.^{6, 7} Generally the amounts of ipecac needed to produce these effects in people are high and can lead to severe side effects. Emetine or its somewhat safer form, dihydroemetine, are reserved for rare cases of people infected with amoebae who are not cured by using anti-amoeba drugs.⁸ Because of the danger involved, ipecac and emetine should never be used without first consulting a physician.

In a preliminary trial, patients with schistosomiasis (a parasitic infection) were treated with a combination of resin and volatile oil of myrrh, in the amount of 10 mg per 2.2 pounds of body weight per day for three days. The cure rate was 91.7% and, of those who did not respond, 76.5% were cured by a second six-day course of treatment, increasing the overall cure rate to 98.1%.⁹

Garlic has been demonstrated to kill parasites, including amoeba¹⁰ and hookworm,¹¹ in test tubes and in animals. Older studies in humans support the use of garlic to treat roundworm, pinworm, and hookworm.¹² However, due to a lack of clinical trials, the amount of garlic needed to treat intestinal parasites in humans is not known.

Wormseed (Chenopodium ambrosioides) is a traditional remedy for infections with worms. However, a study in Mexico found that the powdered herb was not effective at eradicating hookworm, roundworm, or whipworm.¹³

Pumpkin seeds(Cucurbita pepo) have purported effects against tapeworms. Given their safety, they are often recommended as an addition to other, more reliable therapies. In Germany, 200-400 grams are commonly ground and taken with milk and honey, followed by castor oil two hours later.¹⁴ Tapeworms can cause severe illness and should be treated only with medical supervision. In China, pumpkin seeds have been shown to effectively treat acute schistosomiasis, a severe parasitic disease occurring primarily in Asia and Africa that is transmitted by snails.¹⁵ The assistance of a physician is required to help diagnose and treat any suspected intestinal parasite infection.

Several other herbs are traditionally used for treatment of parasites, including male fern (Dryopteris filix mas) root, tansy (Tanacetum vulgare) leaf, wormwood, sweet Annie, black walnut (Juglans nigra) fruit, and cloves (Syzygium aromaticum). Numerous case reports and preliminary studies from the late 1800s and early 1900s have suggested some of these herbs can be helpful for some parasitic infections.¹⁶

In some cultures, it was customary to bathe in chaparral once per year to eliminate skin parasites and to detoxify; however, there is no modern research demonstrating the effectiveness of this use of chaparral.

Anise may have modest antiparasitic actions and has been recommended by some practitioners as a treatment for mild intestinal parasite infections.¹⁷

Curled mint (Mentha crispa) leaf, a close relative of peppermint, has been shown in a preliminary trial to help relieve the symptoms of giardia and amoeba infections in children and adults, as well as to eliminate these parasites in many cases.¹⁸ This study used a tincture of curled mint in the amount of 2 ml three times per day for five days, or 1 ml three times per day for five days for children. Given their close relationship, peppermint could probably be substituted for curled mint when curled mint is unavailable.

Caution: Any herb potent enough to kill parasites could potentially harm the person taking it. Although some of these herbs have antiparasitic actions in test tubes,¹⁹ none has been adequately tested in modern trials for efficacy or safety in humans. Safe and proper use requires the skills of an experienced practitioner.

Are there any side effects or interactions?

Refer to the individual herb for information about any side effects or interactions.

References

1. Miyares C, Hollands I, Castaneda C, et al. Clinical trial with a preparation based on propolis "propolisina" in human giardiasis. Acta Gastroenterol Latinoam 1988;18:195-201.
2. Gupte S. Use of berberine in treatment of giardiasis. Am J Dis Child 1975;129:866.
3. Choudhry VP, Sabir M, Bhide VN. Berberine in giardiasis. Indian Pediatr 1972;9:143-6.
4. Kaneda Y, Torii M, Tanaka T, Aikawa M. In vitro effects of berberine sulphate on the growth and structure of Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Ann Trop Med Parasitol 1991;85:417-25.
5. Okeniyi JAO, Ogunlesi TA, Oyelami OA, Adeyemi LA. Effectiveness of dried Carica papaya seeds against human intestinal parasitosis: a pilot study. J Med Food 2007;10:194-6.
6. Oelkers HA. Studies on anthelmintics. Arzneimittelforschung 1962;121:810-2.
7. Wright CW, Phillipson JD. Natural products and the development of selective antiprotozoal drugs. Phytother Res 1990;4:127-39 [review].
8. Schmeller T, Wink M. Utilization of alkaloids in modern medicine. In: Roberts M, Wink M, eds. Alkaloids-Biochemistry, Ecology and Medicinal Applications. New York: Plenum Press, 1998, 435-59 [review].
9. Sheir Z, Nasr AA, Massoud A, et al. A safe, effective, herbal antischistosomal therapy derived from myrrh. Am J Trop Med Hyg 2001;65:700-4.
10. Mirelman D, Monheit D, Varon S. Inhibition of growth of Entamoeba histolytica by allicin, the active principle of garlic extract (Allium sativum). J Infect Dis 1987;156:243-4.
11. Bastidas CJ. Effect of ingested garlic on Necator americanus and Ancylostoma caninum. Am J Trop Med Hyg 1969;13:920-3.
12. Koch HP, Lawson LD, eds. Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species. Baltimore: Williams & Wilkins, 1996, 173-4.
13. Kliks MM. Studies on the traditional herbal anthelmintic Chenopodium ambrosioides L.: Ethnopharmacological evaluation and clinical field trials. Soc Sci Med 1985;21:879-86.
14. Weiss RF. Herbal Medicine. Beaconsfield, UK: Beaconsfield Publishers Ltd., 1985, 119-20.
15. Chou HC, Ming H. Pumpkin seed (Cucurbita moschata) in the treatment of acute schistosomiasis. Chin Med J 1960;80:115-20.
16. Chopra RN, Chandler AC. Anthelmintics and Their Uses in Medical and Veterinary Practice. Baltimore: Williams & Wilkins Co, 1928.
17. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd., 1985, 203-4.
18. de Santana CF, de Almeida ER, Dos Santos ER, Souza IA. Action of Mentha crispa hydroethanolic extract in patients bearing intestinal protozoan. Fitoterapia 1992;63:409-10.
19. Mendiola J, Bosa M, Perez N, et al. Extracts of Artemisia abrotanum and Artemisia absinthium inhibit growth of Naegleria fowleri in vitro. Trans R Soc Trop Med Hyg 1991;85:78-9.

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Last Review: 01-21-2009

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires February 2010.

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