Metronidazole (Vaginal)

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Also indexed as:

MetroGel Vaginal

Metronidazole (vaginal) is an intravaginal antibiotic used to treat vaginal infections caused primarily by bacteria. Metronidazole is also available as oral and topical medications.

Herbs

Summary of Interactions for Metronidazole Vaginal

Depletion or interference	None known
Adverse interaction	None known
Side effect reduction/prevention	None known
Supportive interaction	Zinc
Reduced drug absorption/bioavailability	None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Supplements

Zinc

Four women whose vaginal infections caused by trichomonas (one-celled parasites) were not responding to oral and vaginal metronidazole treatment alone, improved when a zinc sulfate douche was added.¹ Controlled research is needed to determine if zinc enhances the effects of metronidazole in vaginal infections caused by other organisms.

References

1. Houang ET, Ahmet Z, Lawrence AG. Successful treatment of four patients with recalcitrant vaginal trichomoniasis with a combination of zinc sulfate douche and metronidazole therapy. Sex Transm Dis 1997;24:116-9.

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Last Review: 01-21-2009

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires February 2010.

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