Hydrocodone

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Combination List

Combination drugs:

• Lortab
• Tussionex
• Vicoprofen

Hydrocodone is a narcotic analgesic used in combination products to relieve mild to moderate pain and an antitussive agent to relieve cough and upper respiratory symptoms associated with allergy or cold.

Herbs

Summary of Interactions for Hydrocodone

Depletion or interference	None known
Adverse interaction	None known
Side effect reduction/prevention	None known
Supportive interaction	None known
Reduced drug absorption/bioavailability	None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Other Interactions

Food

Hydrocodone may cause gastrointestinal (GI) upset. Hydrocodone-containing products may be taken with food to reduce or prevent GI upset.¹ A common side effect of narcotic analgesics is constipation.² Increasing dietary fiber (especially vegetables and whole-grain foods) and water intake can ease constipation.

Alcohol

Hydrocodone may cause drowsiness, dizziness, or blurred vision. Alcohol may intensify these effects and increase the risk of accidental injury.³ To prevent problems, people taking hydrocodone should avoid alcohol.

References

1. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242-3v.
2. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242-3v.
3. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242-3v.

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Last Review: 01-21-2009

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