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Propolis is the resinous substance collected by bees from the leaf buds and bark of trees, especially poplar and conifer trees. Bees use the propolis along with beeswax to construct their hives.
Where is it found?
Propolis is available in liquid extract form as well as in capsules and tablets. Topical creams and sprays containing propolis are also available, but whether they closely resemble topical propolis products used in research is unclear.
Health Concerns
Propolis has been used in connection with the following conditions (refer to the individual health concern for complete information):
Deficiency Symptoms
Who is likely to be deficient?
Propolis is not an essential nutrient and no deficiency states have been reported.
Dosage
How much is usually taken?
Most manufacturers recommend 500 mg of oral propolis products once or twice daily. For topical applications, follow label instructions.
Side Effects
Are there any side effects or interactions?
Propolis is generally nontoxic, though allergic reactions have been reported.1 These reactions are typically limited to skin rashes;2 however, as with other bee products (e.g., pollen and royal jelly), more severe allergic reactions are possible. People who are allergic to bee pollen, honey, or conifer and poplar trees should not use propolis unless tested first by an allergy specialist. As the effects of propolis during pregnancy and breast-feeding have not been sufficiently evaluated, women should not use it during these times unless directed to do so by a physician.
At the time of writing, there were no well-known drug interactions with propolis.
References
- Burdock GA. Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 1998;36:347-63 [review].
- Hausen BM, Wollenweber E, Senff H, Post B. Propolis allergy. (I). Origin, properties, usage and literature review. Contact Dermatitis 1987;17:163-70 [review].
Last Review: 01-21-2009

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires February 2010.